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LC3-mHTT-IN-AN1

Cat. No. M9610

All AbMole products are for research use only, cannot be used for human consumption.

LC3-mHTT-IN-AN1 Structure
Size Price Availability Quantity
1mg USD 45 In stock
5mg USD 110 In stock
10mg USD 175 In stock
25mg USD 340 In stock
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Quality Control & Documentation
Biological Activity

LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound, interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Chemical Information
Molecular Weight 411.04
Formula C15H9Br2NO3
CAS Number 486443-73-6
Solubility (25°C) DMSO ≥ 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zhaoyang Li, et al. Nature. Allele-selective Lowering of Mutant HTT Protein by HTT-LC3 Linker Compounds

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