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LB80317 

Cat. No. M30097

All AbMole products are for research use only, cannot be used for human consumption.

LB80317  Structure

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Quality Control & Documentation
Biological Activity

LB80317 is an active metabolite of LB80380 and suppresses the DNA synthesis of HBV with an EC50 of 0.5 μM. LB80317 has antiviral effect and has the potential for chronic hepatitis B treatment.

Chemical Information
Molecular Weight 315.22
Formula C10H14N5O5P
CAS Number 441785-24-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jun Gi Hwang, et al. J Clin Pharmacol. Influence of Renal Function on the Single-Dose Pharmacokinetics of Besifovir, a Novel Antiviral Agent for theTreatment of Hepatitis B Virus Infection

[2] Lung-Yi Mak, et al. Expert Opin Drug Metab Toxicol. Pharmacokinetic evaluation of besifovir for the treatment of HBV infection

[3] Jin Ah Jung, et al. Int J Clin Pharmacol Ther. Pharmacokinetic comparison of the maleate and free base formulations of LB80380, a novel nucleotide analog, in healthy male volunteers

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Keywords: LB80317  supplier, Anti-infection, inhibitors, activators

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