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Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.
| Molecular Weight | 236.1 |
| Formula | C8H11Cl2N3O |
| CAS Number | 103878-83-7 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related Monoamine Oxidase Products |
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| Safinamide Mesylate
Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
| Clorgyline hydrochloride
Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). |
| Guanethidine Hemisulfate
Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. |
| Moclobemide
Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. |
| Nialamide
Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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