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Lanraplenib succinate is a potent, highly selective and orally active splenic tyrosine kinase (SYK) inhibitor and inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor with an IC50 value of 9.5 nM.
| Molecular Weight | 620.64 |
| Formula | C23H25N9O.3/2C4H6O4 |
| CAS Number | 1800047-00-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 83.33 mg/mL |
| Storage | 4°C, dry, sealed |
| Related Syk Products |
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| R-406
R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM. |
| Fostamatinib disodium
Fostamatinib disodium (R788, R-935788) is a potent, ATP-competitive and selective Syk (Spleen tyrosine kinase) inhibitor with IC50 of 41 nM. |
| Fostamatinib
Fostamatinib (R788) is a spleen tyrosine kinase (Syk) inhibitor with IC50 of 41 nM. |
| P505-15 hydrochloride
P505-15 (PRT062607) is a novel, highly selective inhibitor of Syk with IC50 value of 1-2 nM. |
| GS-9973
GS-9973 is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM. |
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Products are for research use only. Not for human use. We do not sell to patients.
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