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Laninamivir

Cat. No. M29117

All AbMole products are for research use only, cannot be used for human consumption.

Laninamivir Structure
Synonym:

R 125489

Price and Availability

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Quality Control & Documentation
Biological Activity

Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively.

Chemical Information
Molecular Weight 346.34
Formula C13H22N4O7
CAS Number 203120-17-6
Form Solid
Solubility (25°C) Water 5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chihiro Suzuki, et al. World J Clin Cases. Laninamivir-induced ischemic enterocolitis: A case report

[2] Magdalena Świerczyńska, et al. Int J Environ Res Public Health. Antiviral Drugs in Influenza

[3] Seizaburo Kashiwagi, et al. Int J Antimicrob Agents. Safety of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate in post-marketing surveillance

[4] Hideyuki Ikematsu, et al. Expert Rev Anti Infect Ther. Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza

[5] Makoto Yamashita. Antivir Chem Chemother. Laninamivir and its prodrug, CS-8958: long-acting neuraminidase inhibitors for the treatment of influenza

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Keywords: Laninamivir, R 125489 supplier, Anti-infection, inhibitors, activators

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