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Lanatoside C is a cardiac glycoside, with IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C inhibits the early processes of the dengue virus replication cycle. Furthermore, Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71. Lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses.
| Molecular Weight | 985.12 |
| Formula | C49H76O20 |
| CAS Number | 17575-22-3 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yujia Xu, et al. Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma
[5] Huairui Shi, et al. Lanatoside C Promotes Foam Cell Formation and Atherosclerosis
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