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Ladostigil (TV-3326) hemitartrate is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with IC50s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hemitartrate exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil hemitartrate can be used for the research of depression and Alzheimer's disease.
| Molecular Weight | 694.77 |
| Formula | C16H20N2O2.1/2C4H6O6 |
| CAS Number | 209394-46-7 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL (ultrasonic) DMSO 50 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related Monoamine Oxidase Products |
|---|
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Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
| Clorgyline hydrochloride
Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). |
| Guanethidine Hemisulfate
Guanethidine Hemisulfate is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. |
| Moclobemide
Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM. |
| Nialamide
Nialamide is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class used as an antidepressant and anxiolytic. |
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