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L685818 

Cat. No. M28438

All AbMole products are for research use only, cannot be used for human consumption.

L685818  Structure

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Quality Control & Documentation
Biological Activity

L685818 is a specific immunophilin ligand. L685818 was neuroregenerative and non-neuroprotective in primary brain cultures. L685818 protects dopaminergic neurons from toxic inhibition of MPP+ and 6-OHDA, reduces tyrosine hydroxylase (TH) loss, and promotes neuronal process regeneration. L685818 is also an antifungal reagent for Cryptococcus neoformans.

Chemical Information
Molecular Weight 808.01
Formula C43H69NO13
CAS Number 143839-74-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Shang-Jin Kim, et al. Biochem Biophys Res Commun. Immunosuppressants inhibit hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells

[2] Helieh S Oz, et al. Med Sci Monit. Effects of immunomodulators on acute Trypanosoma Cruzi infection in mice

[3] X Guo, et al. Eur J Neurosci. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons

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  Catalog
Abmole Inhibitor Catalog




Keywords: L685818  supplier, Antifungal, inhibitors, activators

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