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L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. L-Leucine increases intracellular HIF-1α levels and activates the HIF-1α signaling pathway, and these two effects are mediated by the mTOR signaling pathway. This process results in Ngn3 repression and, consequently, decreases β-cell differentiation.
Cell Prolif. 2024 Jul 02.
Transcription factor EB reprograms branched-chain amino acid metabolism and promotes pancreatic cancer progression via transcriptional regulation of BCAT1
L-Leucine purchased from AbMole
| Molecular Weight | 131.17 |
| Formula | C6H13NO2 |
| CAS Number | 61-90-5 |
| Solubility (25°C) | Water 10 mg/mL |
| Storage | 2-8°C, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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