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L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK. L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%.
| Molecular Weight | 3822.44 |
| Formula | C164H286N66O40 |
| Solubility (25°C) | Water 100 mg/mL |
| Storage | -20°C, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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