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L-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis.
| CAS Number | 9015-68-3 |
| Solubility (25°C) | 0.1 M HCL : 50 mg/mL (ultrasonic and adjust pH to 3 with HCl) |
| Storage | -20°C, protect from light |
[1] Jacek Lubkowski, et al. Structural and biochemical properties of L-asparaginase
[2] Marcela Helena Gambim Fonseca, et al. Circumventing the side effects of L-asparaginase
[3] Faizan Muneer, et al. Microbial L-asparaginase: purification, characterization and applications
[4] Angela Beckett, et al. What makes a good new therapeutic L-asparaginase?
[5] Tahira Batool, et al. A Comprehensive Review on L-Asparaginase and Its Applications
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