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L-759,633

Cat. No. M6888

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L-759,633 Structure

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Quality Control & Documentation
Biological Activity

L-759,633 is a high affinity, selective CB2 receptor agonist (Ki values are 6.4 and 1043 nM for CB2 and CB1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB2 receptors expressed in CHO cells (EC50 = 8.1 nM).

Chemical Information
Molecular Weight 384.59
Formula C26H40O2
CAS Number 174627-50-0
Solubility (25°C) DMSO 9.61 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sabbatini, et al. Mol Cancer Ther. GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers.

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Keywords: L-759,633 supplier, inhibitors, activators

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