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L-701324 is a potent anticonvulsant compound that reduces the propensity to activate the mesolimbic dopaminergic system in rodents. L-701324 showed beneficial effects in animal models of Parkinson's rigidity, but not in animal models of Parkinson's dyskinesia. L-701324 (2.5-40 mg/kg, I.P.) dose-dependently reduced enhanced muscle tone from haloperidol (1-5 mg/kg, I.P.).
| Molecular Weight | 363.79 |
| Formula | C21H14ClNO3 |
| CAS Number | 142326-59-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 36 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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