All AbMole products are for research use only, cannot be used for human consumption.
KU14R has been shown to block the effects of the atypical I(3) agonist efaroxan at the level of the ATP-sensitive K(+) (K(ATP)) channel in isolated pancreatic islet beta cells, but its effects in vivo are not known. KU14R does not act as an antagonist of either efaroxan or S22068 at an imidazoline site in vivo.KU-14R, an I(3)-R antagonist, partially attenuated responses to IAA-RP.
| Molecular Weight | 214.26 |
| Formula | C13H14N2O |
| CAS Number | 189224-48-4 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Insulin Receptor Products |
|---|
| Kaempferitrin
Kaempferitrin is a natural flavonoid glycoside with pain relief, anti-inflammatory, anti-diabetes, anti-tumor and other effects, and can activate insulin signaling. |
| Rhoifolin
RhoifolinRhoifolin is a flavonoid glycoside isolated from the leaves of Guanxi pomelo (Citrus Grandis). Rhoifolin is beneficial to diabetic complications by enhancing adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and translocation of GLUT4. Rhoifolin ameliorates titanium-stimulated osteolysis and attenuates osteoclast formation through ranKL-induced NF-κB and MAPK pathways. |
| Demethylasterriquinone B1
Demethylasterriquinone B1 is a selective insulin RTK activator. |
| S961 TFA
S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 of 0.048 for HIR-A, HIR-B and higF-IR, respectively. 0.027 and 630 nM. |
| Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin, shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
