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KU 59403 

Cat. No. M55924

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KU 59403  Structure

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Quality Control & Documentation
Biological Activity

KU 59403 is a potent ATM inhibitor, with IC50 values of 3 nM, 9.1 μM and 10 μM for ATM, DNA-PK and PI3K, respectively.

Chemical Information
Molecular Weight 564.72
Formula C29H32N4O4S2
CAS Number 845932-30-1
Form Solid
Solubility (25°C) DMSO 10 mg/mL
Storage -20°C, dry, sealed
Related ATM/ATR Products
KU-55933

KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR).

KU-60019

KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM.

VE-821

VE-821 is a highly selective and potent ATR inhibitor with IC50 of 26 nM.

ETP-46464

ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively.

CP-466722

Cp-466722 is a reversible ATM inhibitor with IC50 value of 4.1 μM, but has no effect on PI3K, PIKK family proteins.

  Catalog
Abmole Inhibitor Catalog




Keywords: KU 59403  supplier, ATM/ATR, inhibitors, activators

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