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KT203

Cat. No. M8481

All AbMole products are for research use only, cannot be used for human consumption.

KT203 Structure

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Quality Control & Documentation
Biological Activity

KT203 is a very potent, selective inhibitor of ABHD6 (IC50 = 0.82 nM). KT203 inhibits ABHD6 activity in the liver, but not the brain following ip injection in mice.

Chemical Information
Molecular Weight 466.53
Formula C28H26N4O3
CAS Number 1402612-64-9
Solubility (25°C) DMSO: 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shweta Choudhary, et al. Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

[2] Andrea Manterola, et al. Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis

[3] Ku-Lung Hsu, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)

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  Catalog
Abmole Inhibitor Catalog




Keywords: KT203 supplier, inhibitors, activators

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