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KPH2f is an orally potent dual URAT1/GLUT9 inhibitor, with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively.KPH2f had little effect on OAT1 and ABCG2 (IC50s of 32.14 and 26.74 μM, respectively).
| Molecular Weight | 433.46 |
| Formula | C24H16N3NaO2S |
| CAS Number | 2760615-09-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 16.67 mg/mL |
| Storage | 4°C, dry, sealed |
| Related URAT1 Products |
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| Lesinurad
Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. |
| Verinurad
Verinurad, also known as RDEA3170, is an organic anion transporter URAT1 inhibitor with an IC50 of 25 nM. |
| Dotinurad
Dotinurad is a potent selective urate reabsorption inhibitor. Dotinurad inhibits Urate Transporter 1 (URAT1), IC50 value is 37.2 nM. Dotinurad is used as a uric acid-enhancing excretor. |
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Products are for research use only. Not for human use. We do not sell to patients.
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