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KLK7/ELA2-IN-1

Cat. No. M42346

All AbMole products are for research use only, cannot be used for human consumption.

KLK7/ELA2-IN-1 Structure

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Quality Control & Documentation
Biological Activity

KLK7/ELA2-IN-1 is a potent kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC50s of 6 nM and 55 nM, respectively.

Chemical Information
Molecular Weight 929.11
Formula C46H72N8O12
CAS Number 1122484-55-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Joseph Chavarria-Smith et al. Sci Transl Med. Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis

[2] Erhua Chen et al. Open Med (Wars). Analysis of expression and prognosis of KLK7 in ovarian cancer

[3] Hyunjin Yeo et al. Biochem Biophys Res Commun. EGR-1 acts as a transcriptional activator of KLK7 under IL-13 stimulation

[4] Ilangovan Raju et al. Biol Chem. Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells

[5] T Roelandt et al. Int J Cosmet Sci. LEKTI-1 in sickness and in health

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Keywords: KLK7/ELA2-IN-1 supplier, Elastase, inhibitors, activators

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