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Ki-7 is an A2B adenosine receptor positive allosteric regulator. Ki-7 enhances cAMP accumulation induced by NECA, a non-selective A2B adenosine receptor agonist (EC50=445.8 nM). Ki-7 also enhanced selective A2B adenosine receptor agonist BAY 60-6583 and adenosine-induced cAMP accumulation with EC50 of 2390 nM and 2550 nM, respectively.
| Molecular Weight | 354.41 |
| Formula | C23H18N2O2 |
| CAS Number | 1489263-00-4 |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Irma Nareswari, et al. Med Acupunct. Acupuncture Therapy for Severe Oligoasthenoteratozoospermia
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CGS 21680 hydrochloride is an A2A adenosine receptor agonist with an Ki of 27 nM. |
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Istradefylline (KW-6002) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. |
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CGS 21680 is a selective adenosine receptor agonist for A2A and A3 with Ki of 15 ng/mL and 37 ng/mL, respectively. |
| Norisoboldine
Norisoboldine is an isoquinoline alkaloid which acts as an AhR agonist. |
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