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KH7 is a specific inhibitor of soluble adenylate cyclase (sAC) with IC50 values of 3-10 μM against recombinant sACt proteins (human and others) in cells. KH7 is also an inhibitor of cAMP.
| Molecular Weight | 419.3 |
| Formula | C17H15BrN4O2S |
| CAS Number | 330676-02-3 |
| Form | Solid |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage | -20°C |
| Related Adenylate Cyclase Products |
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| Forskolin
Forskolin is a diterpenoid natural product extracted from the hairy throat sphagnum flower (Coleus forskohlii), and is also a eukaryotic adenylate cyclase (AC) activator, which can increase cAMP levels. In addition, Forskolin can be used as a substitute for Oct4 in the induction and maintenance of pluripotent stem cells in mice and promotes osteoblast differentiation in vitro with potential anti-osteoporotic activity. |
| Bithionol
Bithionol is a potent inhibitor of soluble adenylyl cyclase(sAC) and has antibacterial and anthelmintic properties along with algaecide activity. |
| SQ22536
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. |
| ST034307
ST034307 is a selective inhibitor of adenylyl cyclase 1 (AC1) with IC50 of 2.3 μM, it has analgesic activity. |
| 2',5'-Dideoxyadenosine
2′,5′-Dideoxyadenosine is a cell-permeable adenylyl cyclase inhibitor, IC50 = 2.7 μM in detergent-dispersed rat brain preparations. |
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