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KDU731 

Cat. No. M28673

All AbMole products are for research use only, cannot be used for human consumption.

KDU731  Structure

Price and Availability

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Quality Control & Documentation
Biological Activity

KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo. KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety.

Chemical Information
Molecular Weight 396.4
Formula C22H16N6O2
CAS Number 1610610-48-4
Form Solid
Solubility (25°C) DMSO 83.33 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Miguel A Chavez, et al. Expert Rev Anti Infect Ther. Novel treatment strategies and drugs in development for cryptosporidiosis

[2] Honorine D Ward. Trends Parasitol. New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis

[3] Ujjini H Manjunatha, et al. Nature. A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

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  Catalog
Abmole Inhibitor Catalog




Keywords: KDU731  supplier, PI3K, inhibitors, activators

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