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Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects.
Kaurenoic acid (1, 3, 10 mg/kg; i.g.; single dose) inhibited LPS-induced mechanical and thermal hyperalgesia, suppressed MPO activity, regulated the redox state of mouse paws, inhibited the production of pro-inflammatory/pain cytokines (such as TNF-α, IL-1β, and IL-33), and enhanced the production of anti-inflammatory/analgesic cytokine IL-10 in mice.
| Molecular Weight | 302.45 |
| Formula | C20H30O2 |
| CAS Number | 6730-83-2 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, dry |
[5] Kyun Ha Kim, et al. Phytomedicine. Kaurenoic acid activates TGF-β signaling
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