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KALA is an amphiphilic peptide that forms an α-helical structure. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors.
Sequence: Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala
| Molecular Weight | 3131.82 |
| Formula | C144H248N40O35S |
| CAS Number | 187987-64-0 |
| Solubility (25°C) | Water |
| Storage | Store at ≤-20°C, protect from light, dry, sealed |
[1] Pramit Ghosh, et al. Indian J Dermatol. Epidemiology of Post-Kala-azar Dermal Leishmaniasis
[3] H W Murray. AIDS Patient Care STDS. Kala-azar as an AIDS-related opportunistic infection
[4] L S Prasad. Indian J Pediatr. Kala azar
[5] P Aggarwal, et al. Indian J Pediatr. Kala-azar--new developments in diagnosis and treatment
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