All AbMole products are for research use only, cannot be used for human consumption.
Kaempferol is an inverse agonist of ERRα and ERRγ that inhibits estrogen receptor (ER α) expression in breast cancer cells and induces apoptosis by activating MEK-MAPK in glioblastoma cells and lung cancer cells. It can be used in breast cancer research.
Phytomedicine. 2024 May 4.
Shenling Baizhu powder alleviates non-alcoholic fatty liver disease by modulating autophagy and energy metabolism in high-fat diet-induced rats
Kaempferol purchased from AbMole
J Cell Mol Med. 2020 May;24(9):5168-5184.
A network pharmacology-based approach to explore the effects of Chaihu Shugan powder on a non-alcoholic fatty liver rat model through nuclear receptors
Kaempferol purchased from AbMole
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Source | J Cell Mol Med 2020 May. Figure 8. Kaempferol (Abmole Bioscience, USA) |
| Method | HPLC-MS | |
| Cell Lines | - | |
| Concentrations | - | |
| Incubation Time | - | |
| Results | Kaempferol interacts with 3 amino acids, ARG 288, LEU 330 and SER 342, near the PPARγ active site and forms 4 hydrogen bonds, thus promoting binding. Naringenin formed a network of five hydrogen bonds with PPARγ through 4 amino acids, CYS 285, HIS 440, TYR 327 and LEU 340, near the active site, establishing stable binding |
| Molecular Weight | 286.23 |
| Formula | C15H10O6 |
| CAS Number | 520-18-3 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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