All AbMole products are for research use only, cannot be used for human consumption.
Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity. Juglone irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 µM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.
The compound is unstable in solution and is recommended to be prepared and used immediately.
J Cancer Res Clin Oncol. 2025 Jun 21;151(6):194.
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer
Juglone purchased from AbMole
| Molecular Weight | 174.15 |
| Formula | C10H6O3 |
| CAS Number | 481-39-0 |
| Solubility (25°C) | DMSO 10 mg/mL Ethanol 5 mg/mL |
| Storage | 2-8°C, protect from light, sealed |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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