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JNJ-63576253 (TRC-253) free base is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 free base can be used for the research of castration-resistant prostate cancer (CRPC).
| Molecular Weight | 502.51 |
| Formula | C23H21F3N6O2S |
| CAS Number | 2110426-27-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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