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JNJ-54717793

Cat. No. M21270

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JNJ-54717793  Structure

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Quality Control & Documentation
Biological Activity

JNJ-54717793 is a selective octreotide-1 receptor antagonist used in studies of anxiety disorders, unlike the dual octreotide-1/2 inhibitors and octreotide-2 inhibitors typically used in sleep disorders.

Chemical Information
Molecular Weight 458.41
Formula C22H18F4N6O
CAS Number 1628843-99-1
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cathy Prville, et al. ACS Med Chem Lett. Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793

[2] Pascal Bonaventure, et al. Front Pharmacol. Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation

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Keywords: JNJ-54717793 supplier, OX Receptor, inhibitors, activators

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