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JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
| Molecular Weight | 365.45 |
| Formula | C19H19N5OS |
| CAS Number | 681136-29-8 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related FAAH Products |
|---|
| URB597
URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. |
| PF-3845
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2. |
| Biochanin-A
Biochanin A is A naturally occurring fatty acid amide hydrolase (FAAH) inhibitor that inhibits FAAH in mice, rats and humans with FAAH IC50 of 1.8, 1.4 and 2.4 μM, respectively. |
| FAAH-IN-2
FAAH-IN-2 is a potent FAAH (fatty acid amide hydrolase) inhibitor. |
| PF 04457845
PF 04457845 is a potent and selective irreversible FAAH inhibitor. |
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