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JG-231 

Cat. No. M28715

All AbMole products are for research use only, cannot be used for human consumption.

JG-231  Structure

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Quality Control & Documentation
Biological Activity

JG-231 is an analogue of JG-98 with anticancer effects. JG-231 inhibits the interaction of Hsp70-BAG3. JG-231 inhibits MDA-MB-231 heterograft tumor models of triple negative breast cancer (TNBC).

Chemical Information
Molecular Weight 619.47
Formula C22H18BrCl2N3OS4
CAS Number 1627126-59-3
Form Solid
Solubility (25°C) DMSO 2 mg/mL (ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] Seung-Keun Hong, et al. Int J Mol Sci. Analogs of the Heat Shock Protein 70 Inhibitor MKT-077 Suppress Medullary Thyroid Carcinoma Cells

[2] Pui-Kei Wu, et al. Oncogene. Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability

[3] Hao Shao, et al. J Med Chem. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70)

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  Catalog
Abmole Inhibitor Catalog




Keywords: JG-231  supplier, HSP, inhibitors, activators

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