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Opnurasib (JDQ-443，NVP-JDQ443) is a covalent inhibitor of KRAS G12C.
| Molecular Weight | 526.03 |
| Formula | C29H28ClN7O |
| CAS Number | 2653994-08-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 70 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Ras Products |
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| ZCL278
ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM. |
| Kobe0065
Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD, exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM. |
| K-Ras(G12C) inhibitor 9
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). |
| 6H05 trifluoroacetate
6H05 is a selective and allosteric inhibitor of oncogenic K-Ras(G12C). |
| CASIN
CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. |
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