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Jatrorrhizine chloride

Cat. No. M4457

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Jatrorrhizine chloride Structure
Size Price Availability Quantity
20mg USD 80 In stock
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Quality Control & Documentation
Biological Activity

Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine significantly inhibited 5-HT and NE uptake in synaptosomes at 25 μM and 50 μM. Jatrorrhizine strongly inhibits PMAT-mediated MPP+ uptake with an IC50 value of 1.05 μM.

Chemical Information
Molecular Weight 373.83
Formula C20H20ClNO4
CAS Number 6681-15-8
Solubility (25°C) DMSO 4 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] C W Wright, et al. J Nat Prod. In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids

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Keywords: Jatrorrhizine chloride supplier, AChR/AChE, inhibitors, activators

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