Free shipping on all orders over $ 500

Jaceosidin

Cat. No. M4637

All AbMole products are for research use only, cannot be used for human consumption.

Jaceosidin Structure
Size Price Availability Quantity
1mg USD 55 In stock
5mg USD 120 In stock
10mg USD 190 In stock
20mg USD 290 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Jaceosidin is a flavonoid obtained from Artemisia vestita, which can activate Bax, down-regulate the expression of McL-1 and C-flip, and induce apoptosis of cancer cells. Jaceosidin has anti-cancer and anti-inflammatory effects, which can reduce the level of inflammatory factors, activate NF-κB, and inhibit the expression of COX-2.

Chemical Information
Molecular Weight 330.29
Formula C17H14O7
CAS Number 18085-97-7
Solubility (25°C) DMSO ≥ 36 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuzhou Liu, et al. Protection against Doxorubicin-Related Cardiotoxicity by Jaceosidin Involves the Sirt1 Signaling Pathway

[2] Eunkyo Park, et al. Jaceosidin Ameliorates Insulin Resistance and Kidney Dysfunction by Enhancing Insulin Receptor Signaling and the Antioxidant Defense System in Type 2 Diabetic Mice

[3] Hyemi Lee, et al. Seomae mugwort and jaceosidin attenuate osteoarthritic cartilage damage by blocking IκB degradation in mice

[4] Bushra Nageen, et al. Jaceosidin: A Natural Flavone with Versatile Pharmacological and Biological Activities

[5] Wen-Rong Fu, et al. Bidirectional Regulatory Mechanisms of Jaceosidin on Mitochondria Function: Protective Effects of the Permeability Transition and Damage of Membrane Functions

Related Bcl-2 Products
ABT-263

ABT-263 (Navitoclax) is a potent, orally bioavailable inhibitor of the antiapoptotic Bcl-2 family members Bcl-2, Bcl-x (L), and Bcl-w.

ABT-737

ABT-737 is a potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, in small cell lung cancer.

AT-101

AT-101 (R-(-)-gossypol acetic acid) is a pan small molecule inhibitor of Bcl-2, Bcl-xL, and Mcl-1.

ABT-199

ABT-199 (Venetoclax) is a highly potent, orally bioavailable and BCL-2 inhibitor. ABT-199 is the first inhibitor targeting Bcl-2 and PPI.

TW-37

TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: Jaceosidin supplier, Bcl-2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.