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Izeltabart is a high-affinity humanized antibody targeting ADAM9. Izeltabart can be used as ADC Antibody for site-specific conjugation with Maytansinoid-based DM21-C to synthesize IMGC936, an Antibody-drug Conjugate with strong anti-cancer activity. IMGC936 exhibits cytotoxicity against ADAM9-positive human tumor cell lines and potent antitumor activity in xenograft tumor models.
| CAS Number | 2642078-60-0 |
| Form | Liquid |
| Storage | Store at ≤ -20°C. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws. |
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Products are for research use only. Not for human use. We do not sell to patients.
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