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IW927 is a potent small molecule antagonist that blocks the binding of TNF-α to TNFRc1 with an IC50 value of 50 nM and disrupts TNFα-induced IκB phosphorylation with an IC50 value of 600 nM.
| Molecular Weight | 441.57 |
| Formula | C22H23N3O3S2 |
| CAS Number | 389142-48-7 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TNF Receptor Products |
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| Mesaconitine
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| Hypaconitine
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