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Itolizumab

Cat. No. M24551

All AbMole products are for research use only, cannot be used for human consumption.

Itolizumab Structure
Synonym:

Anti-Human CD6 Recombinant Antibody

Size Price Availability Quantity
100ug USD 190 In stock
1mg USD 330 In stock
5mg USD 880 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.

Chemical Information
CAS Number 1116433-11-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] A García-Lledó, et al. Rev Esp Quimioter. Pharmacological treatment of COVID-19: an opinion paper

[2] Subramanian Loganathan, et al. Expert Opin Biol Ther. Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications

[3] Leelavathy Budamakuntla, et al. Psoriasis (Auckl). Spotlight on itolizumab in the treatment of psoriasis - current perspectives from India

[4] Ankita Srivastava. Indian J Dermatol. Itolizumab in Psoriasis

[5] Sunil Dogra, et al. Expert Opin Biol Ther. Itolizumab, a novel anti-CD6 monoclonal antibody: a safe and efficacious biologic agent for management of psoriasis

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Keywords: Itolizumab, Anti-Human CD6 Recombinant Antibody supplier, inhibitors, activators

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