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ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM.
| Molecular Weight | 494.65 |
| Formula | C26H34N6O2S |
| CAS Number | 1149753-56-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[4] Hua Xu, et al. ACS Chem Biol. PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor
[5] Jingjing Wu, et al. J Hematol Oncol. Second-generation inhibitors of Bruton tyrosine kinase
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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