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Istaroxime hydrochloride

Cat. No. M14239

All AbMole products are for research use only, cannot be used for human consumption.

Istaroxime hydrochloride Structure
Synonym:

PST2744 hydrochloride

Size Price Availability
5mg USD 280 Out of stock
10mg USD 380 Out of stock
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Quality Control & Documentation
Biological Activity

Istaroxime hydrochloride is a Na+/K+-ATPase inhibitor (IC50=0.11 μM) and a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator.

Chemical Information
Molecular Weight 396.95
CAS Number 374559-48-5
Form Solid
Solubility (25°C) DMSO ≥ 45 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Marcella Rocchetti, et al. Modulation of sarcoplasmic reticulum function by PST2744 [istaroxime; (E,Z)-3-((2-aminoethoxy)imino) androstane-6,17-dione hydrochloride)] in a pressure-overload heart failure model

[2] Marcella Rocchetti, et al. Modulation of sarcoplasmic reticulum function by Na+/K+ pump inhibitors with different toxicity: digoxin and PST2744 [(E,Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride]

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Keywords: Istaroxime hydrochloride, PST2744 hydrochloride supplier, Sodium Channel, inhibitors, activators

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