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Isoxepac

Cat. No. M30295

All AbMole products are for research use only, cannot be used for human consumption.

Isoxepac Structure
Synonym:

HP 549

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Quality Control & Documentation
Biological Activity

Isoxepac (HP 549) is a nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory, analgesic and antipyretic activity. Isoxepac has been studied in rat, rabbit, dog, rhesus monkey, etc.

Chemical Information
Molecular Weight 268.26
Formula C16H12O4
CAS Number 55453-87-7
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] W J Honig, et al. J Clin Pharmacol. Analgesic effect of isoxepac on postmeniscectomy pain: a controlled trial

[2] J Scott, et al. Rheumatol Rehabil. Analgesic action of isoxepac

[3] L B Svendsen, et al. Scand J Rheumatol. A comparison of the effects of HP 549 (Isoxepac), indomethacin and acetylsalicylic acid (Aspirin) on gastric mucosa in man

[4] L S Gerlis, et al. Rheumatol Rehabil. Isoxepac in rheumatoid arthritis: a double-blind comparison with aspirin

[5] H P Illing, et al. Drug Metab Dispos. Species differences in the disposition and metabolism of 6,11-dihydro-11-oxodibenz[be]oxepin-2-acetic acid (isoxepac) in rat, rabbit, dog, rhesus monkey, and man

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Keywords: Isoxepac, HP 549 supplier, inhibitors, activators

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