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Isoscopoletin

Cat. No. M4789

All AbMole products are for research use only, cannot be used for human consumption.

Isoscopoletin Structure
Synonym:

6-Hydroxy-7-methoxycoumarin

Size Price Availability Quantity
5mg USD 75 In stock
10mg USD 120 In stock
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Quality Control & Documentation
Biological Activity

Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.

Product Citations
Chemical Information
Molecular Weight 192.17
Formula C10H8O4
CAS Number 776-86-3
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yangyang Hui, et al. Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action

[2] Houaria Bendjedou, et al. A new ionone derivative from Lycium intricatum Boiss. (Solanaceae)

[3] Risto O Juvonen, et al. Metabolism of Scoparone in Experimental Animals and Humans

[4] P E McGovern, et al. Anticancer activity of botanical compounds in ancient fermented beverages (review)

[5] Michael Adams, et al. Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi

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Keywords: Isoscopoletin, 6-Hydroxy-7-methoxycoumarin supplier, Anti-infection, inhibitors, activators

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