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Isobavachalcone

Cat. No. M4844

All AbMole products are for research use only, cannot be used for human consumption.

Isobavachalcone Structure
Synonym:

Corylifolinin; Isobacachalcone

Size Price Availability Quantity
1mg USD 25 In stock
5mg USD 65 In stock
10mg USD 110 In stock
25mg USD 220 In stock
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Quality Control & Documentation
Biological Activity

Isobavachalcone (Corylifolinin) is an inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Isobavachalcone exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Isobavachalcone (Corylifolinin) displays DNA strand-scission (cleaving) activity. Isobavachalcone hows antifungal activity.

Protocol (for reference only)
Cell Experiment
Cell lines E. aerogenes EA298
Preparation method The lowest MIC values for diospyrone (4 μg/ml) and isobavachalcone (8 μg/ml) were recorded for E. coli AG100A and E. aerogenes EA298, respectively.
Concentrations 8 μg/ml
Incubation time 24 h
Animal Experiment
Animal models male C57BL/6 mice
Formulation LPS
Dosages 50 and 10 mg/kg/day
Administration gavage
Chemical Information
Molecular Weight 324.37
Formula C20H20O4
CAS Number 20784-50-3
Solubility (25°C) 11 mg/mL in DMSO
Storage 2-8°C, protect from light
References

[1] Jing H, et al. PLoS One. Isobavachalcone Attenuates MPTP-Induced Parkinson's Disease in Mice by Inhibition of Microglial Activation through NF-κB Pathway.

[2] Ohno O, et al. Biosci Biotechnol Biochem. Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells.

[3] Kuete V, et al. Antimicrob Agents Chemother. Efflux pumps are involved in the defense of Gram-negative bacteria against the natural products isobavachalcone and diospyrone.

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Keywords: Isobavachalcone, Corylifolinin; Isobacachalcone supplier, Autophagy, inhibitors, activators

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