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Ishophloroglucin A

Cat. No. M18517

All AbMole products are for research use only, cannot be used for human consumption.

Ishophloroglucin A Structure
Synonym:

IPA

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10mg USD 780 In stock
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Biological Activity

Ishophloroglucin A, isolated from Ishige okamurae, is a potent PTP1B inhibitor with IC50 of 0.43 μM, inhibits adipogenesis in 3T3-L1 adipocytes.

Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models Male CrljOri:CD1 (ICR) mice (9-week-old, 33 ± 3 g)
Formulation IPA were dissolved in saline
Dosages 2 mg/kg/day, for 28 days
Administration orally
Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Seung Tae Im, et al. Fitoterapia. Ishophloroglucin A, a potent PTP1B inhibitor isolated from brown alga Ishige okamurae inhibits adipogenesis in 3T3-L1 adipocytes

[2] Hye-Won Yang, et al. Mar Drugs. Ishophloroglucin A, Isolated from Ishige okamurae, Alleviates Dexamethasone-Induced Muscle Atrophy through Muscle Protein Metabolism In Vivo

[3] Xining Li, et al. Mar Drugs. Ishophloroglucin A Isolated from Ishige okamurae Suppresses Melanogenesis Induced by α-MSH: In Vitro and In Vivo

[4] Hye-Won Yang, et al. Mar Drugs. Effect of Ishophloroglucin A, A Component of Ishige okamurae, on Glucose Homeostasis in the Pancreas and Muscle of High Fat Diet-Fed Mice

[5] K H N Fernando, et al. Int J Mol Sci. Ishige okamurae Extract and Its Constituent Ishophloroglucin A Attenuated In Vitro and In Vivo High Glucose-Induced Angiogenesis

[6] BoMi Ryu, et al. Mar Drugs. Ishophloroglucin A, a Novel Phlorotannin for Standardizing the Anti-α-Glucosidase Activity of Ishige okamurae

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Keywords: Ishophloroglucin A, IPA supplier, Others, inhibitors, activators

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