Free shipping on all orders over $ 500

Ipsapirone

Cat. No. M4858

All AbMole products are for research use only, cannot be used for human consumption.

Ipsapirone Structure
Synonym:

TVX Q 7821

Size Price Availability Quantity
5mg USD 80 In stock
10mg USD 120 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Ipsapirone (TVX Q 7821) is a partial agonist of 5-HT1A receptor and also shows antagonism to 5-HT1A receptor. It also showed inhibition of 5-HT2 and α 1-adrenergic activity only at high doses.

Chemical Information
Molecular Weight 401.48
Formula C19H23N5O3S
CAS Number 95847-70-4
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Damian Kułaga, et al. Radioligand and computational insight in structure - Activity relationship of saccharin derivatives being ipsapirone and revospirone analogues

[2] K Wedzony, et al. Ipsapirone enhances the dopamine outflow via 5-HT1A receptors in the rat prefrontal cortex

[3] M K Sanghera, et al. Ipsapirone and 1-(2-pyrimidinyl)-piperazine increase rat locus coeruleus noradrenergic activity

[4] R J Fanelli, et al. Ipsapirone: a novel anxiolytic and selective 5-HT1A receptor ligand

[5] P A Rittenhouse, et al. Comparison of neuroendocrine and behavioral effects of ipsapirone, a 5-HT1A agonist, in three stress paradigms: immobilization, forced swim and conditioned fear

Related 5-HT Receptor Products
Granisetron hydrochloride

Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity.

Sumatriptan succinate

Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.

Vortioxetine hydrobromide

Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro.

Prucalopride

Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties.

(1S-cis)-Milnacipran Hydrochloride

(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

  Catalog
Abmole Inhibitor Catalog




Keywords: Ipsapirone, TVX Q 7821 supplier, 5-HT Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.