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Ipratropium bromide is a muscarinic antagonist, bronchodilator, N-Isopropyl salt of atropine. In anaesthetised guinea-pigs, bronchoconstriction induced by vagal nerve stimulation was potentiated by low doses of the antimuscarinic bronchodilator drug, ipratropium (0.01-1.0 ug/kg); the maximum effect was obtained with 1.0 ug/kg which doubled the bronchoconstriction. When the dose was increased above 1.0 ug/kg potentiation no longer occurred; instead the vagally induced bronchoconstriction was antagonised.<
| Molecular Weight | 412.37 |
| Formula | C20H30BrNO3 |
| CAS Number | 22254-24-6 |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Keri Wellington. Ipratropium bromide HFA
[3] No authors listed. Nurs Times. Ipratropium bromide
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