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IPR-803

Cat. No. M14533

All AbMole products are for research use only, cannot be used for human consumption.

IPR-803 Structure

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Quality Control & Documentation
Biological Activity

IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity.

Chemical Information
Molecular Weight 453.49
CAS Number 892243-35-5
Solubility (25°C) DMSO 7.69 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Timmy Mani, et al. Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis

[2] May Khanna, et al. Targeting multiple conformations leads to small molecule inhibitors of the uPAR·uPA protein-protein interaction that block cancer cell invasion

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  Catalog
Abmole Inhibitor Catalog




Keywords: IPR-803 supplier, Serine/Threonine Protease, inhibitors, activators

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