All AbMole products are for research use only, cannot be used for human consumption.
Ionomycin causes a rapid rise in cytosolic Ca2+ that is due to both a release of cytosolic Ca2+ stores and Ca2+ influx. Ionomycin also activates (2 microM) and primes (20-200 nM) the PMN oxidase. Ionomycin is shown to be an effective ionophore for Ca2+ in rat liver mitochondria. DNA and protein analysis in Ionomycin (SQ23377)-treated cultures revealed DNA fragmentation and PARP cleavage to an 85-kDa fragment typical of caspase-mediated apoptosis. Three hours after addition of ionomycin, the percentage of early apoptotic cells approximately doubles. Necrosis could be detected in ~1-5% of the Ionomycin (SQ23377) treated cells as supported by simultaneously positive fluorescein labeling and propidium iodide uptake.
Adv Sci (Weinh). 2024 Jan;11(4):e2305175.
Single-Cell Atlas of Human Ovaries Reveals The Role Of The Pyroptotic Macrophage in Ovarian Aging
Ionomycin (Calcium salt) purchased from AbMole
Nat Commun. 2023 Mar 23;14(1):1606.
Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field
Ionomycin (Calcium salt) purchased from AbMole
Neurochem Res. 2023 Feb;48(2):447-457.
Ca2+ Regulates Autophagy Through CaMKKβ/AMPK/mTOR Signaling Pathway in Mechanical Spinal cord Injury: An in vitro Study
Ionomycin (Calcium salt) purchased from AbMole
Hematol Oncol. 2023 Jul 26.
Magnesium enhances the graft-versus-tumor effect of donor lymphocytic infusion on hematologic malignancies
Ionomycin (Calcium salt) purchased from AbMole
Front Immunol. 2022 May 23;13:866638.
A Novel STAT3 Gain-of-Function Mutation in Fatal Infancy-Onset Interstitial Lung Disease
Ionomycin (Calcium salt) purchased from AbMole
| Molecular Weight | 747.07 |
| Formula | C41H71O9.Ca |
| CAS Number | 56092-82-1 |
| Solubility (25°C) | DMSO ≥ 10 mg/mL |
| Storage | -20°C, dry, protect from light, sealed |
[2] Chatila T, et al. J Immunol. Mechanisms of T cell activation by the calcium ionophore ionomycin.
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| Azelnidipine
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| Catharanthine
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| Cinepazide maleate
Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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