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Interferon alfa

Cat. No. M25335

All AbMole products are for research use only, cannot be used for human consumption.

Interferon alfa Structure

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Quality Control & Documentation
Biological Activity

Interferon alfa is a type I interferon that activates novel genes and exerts potent antiviral and antiproliferative activity on target cells. Signaling by Interferon alfa requires receptor-dependent activation of Stat1 and Stat2 to form a heterodimeric STAT that binds to the DNA-binding protein IRF-9 (p48) and forms ISGF-3 (IFN-stimulated gene factor 3). The driver genes are then further activated by ISGF-3 to achieve antiviral function.

Chemical Information
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Fu-Kui Zhang. Hepatobiliary Pancreat Dis Int. Interferon-alfa in the treatment of chronic hepatitis B

[2] Michele Baccarani, et al. Semin Hematol. Interferon-alfa for chronic myeloid leukemia

[3] G C Farrell. Hepatology. Therapy of hepatitis C: interferon alfa-n1 trials

[4] C D Williams, et al. Br J Hosp Med. Interferon alfa-2a

[5] R B Chambers, et al. J Am Osteopath Assoc. Interferon alfa-associated retinopathy

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Keywords: Interferon alfa supplier, inhibitors, activators

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