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Ingliforib

Cat. No. M28965

All AbMole products are for research use only, cannot be used for human consumption.

Ingliforib Structure
Synonym:

CP 368296; GPi 296

Size Price Availability Quantity
1mg USD 90 In stock
5mg USD 195 In stock
10mg USD 310 In stock
25mg USD 545 In stock
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Quality Control & Documentation
Biological Activity

Ingliforib (CP 368296) is a glycogen phosphorylase inhibitor, with IC50s of 52, 352 and 150 nM for liver, muscle and brain glycogen phosphorylase, and has cardioprotective activity.

Chemical Information
Molecular Weight 457.91
Formula C23H24ClN3O5
CAS Number 186392-65-4
Form Solid
Solubility (25°C) DMSO 130 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Youde Wang, et al. Molecules. Computational Insights into Novel Inhibitor N-(3-( tert-Butylcarbamoyl)-4-methoxyphenyl)-indole and Ingliforib Specific against GP Isoenzyme Dimers Interaction Mechanism

[2] Zhiwei Yan, et al. Bioorg Chem. Discovery of novel heterocyclic derivatives as potential glycogen phosphorylase inhibitors with a cardioprotective effect

[3] Paul Nkansah, et al. J Control Release. Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs

[4] W Ross Tracey, et al. Am J Physiol Heart Circ Physiol. Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor

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Keywords: Ingliforib, CP 368296; GPi 296 supplier, inhibitors, activators

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