IDO5L

Cat. No. M2720

All AbMole products are for research use only, cannot be used for human consumption.

Synonym:

INCB14943; INCB024360 analogue

Size	Price	Availability
5mg	USD 30	In stock
10mg	USD 50	In stock
50mg	USD 150	In stock
100mg	USD 250	In stock

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IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM.

Animal Experiment
Animal models	Mice bearing GM-CSF-secreting B16 tumors
Formulation	5% DMA, 47.5% propylene glycol
Dosages	75 mg/kg b.i.d
Administration	s.c.

Molecular Weight	271.64
Formula	C9H7ClFN5O2
CAS Number	914471-09-3
Solubility (25°C)	DMSO ≥ 30 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related IDO Products
IDO-IN-2 (NLG-919 Analogue) NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with K_i/EC50 of 7 nM/75 nM.
Coptisine Coptisine, an alkaloid isolated from Coptis, is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM.
Coptisine chloride Coptisine chloride is an effective and non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. Coptisine chloride is an effective H1N1 neuraminidase (NA-1) inhibitor with IC50 of 104.6 μg/mL, which can be used for influenza A virus (H1N1) infection.
Coptisine-Sulfate Coptisine Sulfate is an alkaloid isolated from coptis coptidis. It is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM.
Palmatine Palmatine is an orally active and irreversible IDO-1 inhibitor. Palmatine ameliorates colitis induced by Dextran Sulphate Sodium Salt (DSS) by reducing colon injury, preventing intestinal microbiome imbalance and regulating tryptophan catabolism. Palmatine has potential for colitis research.

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