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Inaxaplin

Cat. No. M25423

All AbMole products are for research use only, cannot be used for human consumption.

Inaxaplin Structure
Synonym:

VX-147

Size Price Availability Quantity
5mg USD 158 In stock
10mg USD 248 In stock
25mg USD 397 In stock
50mg USD 569 In stock
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Quality Control & Documentation
Biological Activity

Inaxaplin (VX-147) is a first-in-class, orally active apolipoprotein L1 (APOL1) function inhibitor. Inaxaplin can be used for the research of kidney disease.

Chemical Information
Molecular Weight 417.38
Formula C21H18F3N3O3
CAS Number 2446816-88-0
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ogo Egbuna, et al. N Engl J Med. Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants. Reply

[2] Maria Jose Soler, et al. N Engl J Med. Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants

[3] Rasheed Gbadegesin, et al. Nat Rev Nephrol. Inaxaplin for the treatment of APOL1-associated kidney disease

[4] Ogo Egbuna, et al. N Engl J Med. Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants

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Keywords: Inaxaplin, VX-147 supplier, inhibitors, activators

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