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Immepip dihydrobromide

Cat. No. M7856

All AbMole products are for research use only, cannot be used for human consumption.

Immepip dihydrobromide Structure

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Quality Control & Documentation
Biological Activity

Immepip is a H3 and H4 histamine receptor agonist. Immepip is a selective H3 agonist equipotent to (R)-α-methylhistamine and also effective in vitro and in vivo. It is devoid of side activities elicited at H1 and α2 receptors and 5-HT3 receptors.

Chemical Information
Molecular Weight 327.06
Formula C9H17N3Br2
CAS Number 164391-47-3
Solubility (25°C) Water: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Manuel Pinacho-Garca, et al. Further evidence for the role of histamine H3, but not H1, H2 or H4, receptors in immepip-induced inhibition of the rat cardioaccelerator sympathetic outflow

[2] Tunyu Jian, et al. TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

[3] Hossein Amini-Khoei, et al. Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice

[4] Guadalupe Manrique-Maldonado, et al. Pharmacological evidence that histamine H3 receptors inhibit the vasodepressor responses by selective stimulation of the rat perivascular sensory CGRPergic outflow

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Keywords: Immepip dihydrobromide supplier, inhibitors, activators

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